• Successful therapy depends on locating the ideal site for delivery of therapy
• Current methods of myocardial characterization and anatomical guidance are not adequate
• Our novel method is based on the biological characterization of cardiac tissue as defined by uptake of molecularly-targeted radiotracers
high resolution images and 3D movie of the heart using a radiotracer that targets sympathetic activity. We observed diffuse activity in the LV and focal activity in areas of the atria that represent ganglionic plexi. Studies suggests an added benefit of ablating these plexi in combination with pulmonary vein isolation for treatment of recurrent A-fib. Our detector-injector catheter may locate and ablate these plex
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